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Comment
. 2009 Jun 26;34(6):637-9.
doi: 10.1016/j.molcel.2009.06.005.

The guardian recruits cops: the p53-p21 axis delegates prosurvival duties to the Keap1-Nrf2 stress pathway

Michel B Toledano  1
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The guardian recruits cops: the p53-p21 axis delegates prosurvival duties to the Keap1-Nrf2 stress pathway

Michel B Toledano. Mol Cell. .
Free article

Abstract

In this issue of Molecular Cell, Zhang and colleagues (Chen et al., 2009) report their identification of p21 as a positive regulator of Nrf2, which extends p53 prosurvival functions through recruitment of a master stress-response regulator.

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