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Review
. 2009:521:55-70.
doi: 10.1007/978-1-60327-815-7_4.

Checkpoint regulation of DNA replication

Erik Boye  1 , Henriette C Skjølberg, Beáta Grallert
Affiliations
Review

Checkpoint regulation of DNA replication

Erik Boye et al. Methods Mol Biol. 2009.

Abstract

We discuss the mechanisms regulating entry into and progression through S phase in eukaryotic cells. Methods to study the G1/S transition are briefly reviewed and an overview of G1/S-checkpoints is given, with particular emphasis on fission yeast. Thereafter we discuss different aspects of the intra-S checkpoint and introduce the main molecular players and mechanisms.

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