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. 2009 Jun 26;137(7):1179-81.
doi: 10.1016/j.cell.2009.06.005.

Ironing out a midlife crisis

Sandra Viviana Vergara  1 , Dennis J Thiele
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Ironing out a midlife crisis

Sandra Viviana Vergara et al. Cell. .
Free article

Abstract

There is a strong correlation between age, genomic instability, and the development of cancer. Working in yeast, Veatch et al. (2009) now propose that defects in the biogenesis of iron-sulfur clusters arising as a consequence of mitochondrial dysfunction contribute to the increase in genomic instability as cells age.

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