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. 2004 Jun 15;2(2):103-8.
doi: 10.1186/1617-9625-2-2-103.

Smoking habits among patients diagnosed with oral lichen planus

Meir Gorsky  1 , Joel B Epstein, Haya Hasson-Kanfi, Eliezer Kaufman
Affiliations

Smoking habits among patients diagnosed with oral lichen planus

Meir Gorsky et al. Tob Induc Dis. .

Abstract

Introduction: Oral lichen planus (OLP) is one of the most common dermatologic diseases that manifests in the oral cavity. The purpose of this study was to evaluate the association between smoking habits and the clinical subtypes of OLP.

Methods: Oral findings and smoking data from 187 charts of OLP patients from an oral medicine clinic was reviewed and compared to data from 76 matched control patients.

Results and discussion: Ninety-three patients were diagnosed with reticular OLP, 55 with atrophic and 39 with erosive forms of the disease. Symptomatic OLP occurred in 63.6% of patients. Fewer cases of reticular OLP were symptomatic than erosive OLP (p < 0.001). Significantly fewer OLP patients smoked than the control group (16% versus 25%) (p = 0.04). More patients with reticular OLP smoked than those with atrophic and erosive OLP (p = 0.002). It is hypothesized that the heat and irritation of smoking may aggravate symptomatic OLP lesions, and the risk of malignant transformation associated with tobacco use may play a role in patients stopping tobacco use. Because there were fewer smokers in patients with OLP, and because OLP carries an increased malignant risk, transformation of OLP may be due to a different etiology and of a different pathogenesis than squamous cell carcinoma not arising from lichen planus. Close follow-up of patients with OLP is indicated.

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Figures

Figure 1
Figure 1
The intensity of symptoms in subtypes of oral lichen planus.
Figure 2
Figure 2
Smoking habits in the control group and the general population (percentage).
Figure 3
Figure 3
Smoking habits in patients with symptomatic oral lichen planus.
See this image and copyright information in PMC

References

    1. Axell T. A prevalence study of oral mucosal lesions in an adult Swedish population. Odontologisk Revy. 1976;27:1–103. - PubMed
    1. Kleinman DV, Swango PA, Niessen LC. Epidemiologic studies of oral mucosal conditionsmethodologic issues. Community Dentistry and Oral Epidemiology. 1991;19:129–140. doi: 10.1111/j.1600-0528.1991.tb00128.x. - DOI - PubMed
    1. Silverman S, Gorsky M, Lozada-Nur F, Giannotti K. A prospective study of findings and management in 214 patients with oral lichen planus. Oral Surgery, Oral Medicine, Oral Pathology. 1991;72:665–670. doi: 10.1016/0030-4220(91)90007-Y. - DOI - PubMed
    1. Gorsky M, Raviv M, Moskona D, Laufer M, Bodner L. Clinical characteristics and treatment of patients with oral lichen planus in Israel. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics. 1996;82:644–649. doi: 10.1016/S1079-2104(96)80439-2. - DOI - PubMed
    1. Silverman S, Gorsky M, Lozada-Nur F. A prospective follow-up study of 570 patients with oral lichen planus: Persistence, remission, and malignant association. Oral Surgery, Oral Medicine, Oral Pathology. 1985;60:30–34. doi: 10.1016/0030-4220(85)90210-5. - DOI - PubMed

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