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Review
. 1991 Aug;16(8):281-2.
doi: 10.1016/0968-0004(91)90115-c.

Hexokinase and 'glucokinase' in liver metabolism

A Cornish-Bowden  1 , M L Cárdenas
Affiliations
Review

Hexokinase and 'glucokinase' in liver metabolism

A Cornish-Bowden et al. Trends Biochem Sci. 1991 Aug.

Abstract

Rat liver contains four hexokinase isoenzymes, one of which, despite often being called 'glucokinase', is no more specific for glucose than the others. However, it does differ from them in displaying a sigmoid kinetic response to glucose, requiring much higher glucose concentrations for activity, and being insensitive to physiological concentrations of glucose 6-phosphate.

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