Reflections on miR-ing effects in metastasis
- PMID: 19573805
- DOI: 10.1016/j.ccr.2009.06.013
Reflections on miR-ing effects in metastasis
Abstract
In a recent issue of Cell, Valastyan et al. demonstrate that miR-31 can regulate multiple steps in the metastatic cascade independent of confounding effects on primary tumor development. These data have potential to provide biomarkers for prognosis and novel targets for intervention in this most lethal aspect of malignancy.
Comment on
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A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis.Cell. 2009 Jun 12;137(6):1032-46. doi: 10.1016/j.cell.2009.03.047. Cell. 2009. Retraction in: Cell. 2015 Apr 9;161(2):417. doi: 10.1016/j.cell.2015.03.047. PMID: 19524507 Free PMC article. Retracted.
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