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Randomized Controlled Trial
. 2009 Oct 1;104(3):212-9.
doi: 10.1016/j.drugalcdep.2009.04.018. Epub 2009 Jul 1.

A "community-friendly" version of integrated group therapy for patients with bipolar disorder and substance dependence: a randomized controlled trial

Roger D Weiss  1 , Margaret L Griffin, William B Jaffee, Rachel E Bender, Fiona S Graff, Robert J Gallop, Garrett M Fitzmaurice
Affiliations
Randomized Controlled Trial

A "community-friendly" version of integrated group therapy for patients with bipolar disorder and substance dependence: a randomized controlled trial

Roger D Weiss et al. Drug Alcohol Depend. .

Abstract

Background: Integrated group therapy, a new treatment for patients with bipolar disorder and substance use disorder, has previously been found to be efficacious in reducing substance use, but its length (20 sessions) and need for highly trained therapists may limit its adoption in substance use disorder community treatment programs. This paper compares a briefer (12 session) version of integrated group therapy, led by substance use disorder counselors without previous cognitive-behavioral training or bipolar disorder experience, to group drug counseling.

Methods: Sixty-one patients with bipolar disorder and substance dependence, taking mood stabilizers, were randomized to 12 sessions of integrated group therapy (n=31) or group drug counseling (n=30).

Results: Analyses of primary outcomes showed trends favoring integrated group therapy, with greater reduction in substance use during follow-up and a greater decline in risk of mood episodes during treatment. Secondary analyses favored integrated group therapy, with a significantly greater likelihood of achieving total abstinence, a significantly shorter time to the first abstinent month, and a significantly greater likelihood of achieving a "good clinical outcome" (a composite measure encompassing both substance use and mood simultaneously).

Conclusions: A shortened version of integrated group therapy can be delivered successfully by substance use disorder counselors, with better overall outcomes than those achieved with group drug counseling.

Trial registration: ClinicalTrials.gov NCT00227838.

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Figures

Figure 1
Figure 1
Study flow chart
Figure 2
Figure 2
Treatment condition over time by days of substance use (upper panel) and by time to first abstinent month (lower panel; N=61). IGT = Integrated Group Therapy, GDC = Group Drug Counseling
See this image and copyright information in PMC

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