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. 2009 Oct;42(15):1585-8.
doi: 10.1016/j.clinbiochem.2009.06.020. Epub 2009 Jul 2.

Use of cyst fluid CEA, CA19-9, and amylase for evaluation of pancreatic lesions

Christine L H Snozek  1 , Ranjan C Mascarenhas, Dennis J O'Kane
Affiliations

Use of cyst fluid CEA, CA19-9, and amylase for evaluation of pancreatic lesions

Christine L H Snozek et al. Clin Biochem. 2009 Oct.

Abstract

Objectives: The study goals were development of reference intervals and an interpretive algorithm for pancreatic cyst fluid tumor markers.

Design and methods: 442 pancreatic cyst fluids were tested for CEA, CA19-9, and amylase.

Results: CEA>30 ng/mL discriminates mucinous from non-mucinous cysts. After CEA analysis, amylase and CA19-9 segregate non-mucinous and mucinous subtypes, respectively.

Conclusions: Pancreatic cyst fluid tumor markers supplement other diagnostic measures. This study provides estimated reference intervals and an algorithm for interpretation.

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