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. 1991 Dec 15;112(6):635-46.
doi: 10.1016/s0002-9394(14)77269-1.

Bone marrow transplant retinopathy

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Bone marrow transplant retinopathy

P F Lopez et al. Am J Ophthalmol. .

Erratum in

  • Am J Ophthalmol 1992 May 15;113(5):616

Abstract

Five of eight patients (62%) who survived at least six months after autologous or allogeneic bone marrow transplantation for acute leukemia developed occlusive microvascular retinopathy. Treatable retinal microangiopathy included a high incidence (80%) of clinically significant macular edema and one case of proliferative retinopathy with subhyaloid hemorrhage. The bone marrow transplant protocol required high-dose cytarabine hydrochloride and 1,200 cGy of total body irradiation. The development of radiation retinopathy after such low doses of teletherapy suggests that high-dose chemotherapy may increase the susceptibility for the development of retinopathy at otherwise safe radiation doses.

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Comment in

  • Bone marrow transplant retinopathy.
    Bernauer W, Gratwohl A. Bernauer W, et al. Am J Ophthalmol. 1992 May 15;113(5):604-5. doi: 10.1016/s0002-9394(14)74751-8. Am J Ophthalmol. 1992. PMID: 1637410 No abstract available.

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