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. 2009 Apr;32(2):193-8.

Prevalence of viral hepatitis and molecular analysis of HBV among voluntary blood donors in west Iran

Abbas Doosti  1 , Samad Amini-Bavil-Olyaee, Elaheh Tajbakhsh, Ahmad Adeli, Fereidoun Mahboudi
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  • PMID: 19579699
Free article

Prevalence of viral hepatitis and molecular analysis of HBV among voluntary blood donors in west Iran

Abbas Doosti et al. New Microbiol. 2009 Apr.
Free article

Abstract

To determine the prevalence of viral hepatitis infection and hepatitis B virus (HBV) molecular characterization, 11,200 blood donors from citizens of Shahrekord (a city located in west of Iran) were investigated. Results showed HBsAg-positive in 1.78% of persons (n=200), anti-HDV-positive in 3% of HBsAg-positive cases (n=6) and anti-HCV-positive in 0.67% of donors (n=76). HBV phylogenetic analysis disclosed HBV genotype D, sub-genotype D1, and subtype ayw2. Amino acid mapping of the HBV pol region revealed various HBV drug-resistance mutations though donors had no antiviral therapy. In conclusion, this study demonstrated notable viral hepatitis seroprevalence rate in blood donors in west of Iran.

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