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. 2009 Jul;4(7):411-4.
doi: 10.1038/nnano.2009.175. Epub 2009 Jun 28.

Evaluation of nanoparticle immunotoxicity

Marina A Dobrovolskaia  1 , Dori R Germolec, James L Weaver
Affiliations

Evaluation of nanoparticle immunotoxicity

Marina A Dobrovolskaia et al. Nat Nanotechnol. 2009 Jul.

Abstract

The pharmaceutical industry is developing increasing numbers of drugs and diagnostics based on nanoparticles, and evaluating the immune response to these diverse formulations has become a challenge for scientists and regulatory agencies alike. An international panel of scientists and representatives from various agencies and companies reviewed the imitations of current tests at a workshop held at the National Cancer Institute in Frederick, Maryland. This article outlines practical strategies for identifying and controlling interferences in common evaluation methods and the implications for regulation.

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References

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