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. 2007 Oct;11(4):216-8.

Prevalence of musculoskeletal disorders in patients with type 2 diabetes mellitus: a pilot study

I Douloumpakas  1 , A Pyrpasopoulou, A Triantafyllou, Ch Sampanis, S Aslanidis
Affiliations

Prevalence of musculoskeletal disorders in patients with type 2 diabetes mellitus: a pilot study

I Douloumpakas et al. Hippokratia. 2007 Oct.

Abstract

Background: Diabetes mellitus is associated with a variety of musculoskeletal disorders. The prevalence of connective tissue disorders in these patients has increased in the recent years affecting significantly their quality of life.

Methods-results: We conducted a pilot study including 208 sequentially selected patients with type 2 diabetes mellitus regularly followed-up at the Diabetes Center of the Hippokration University Hospital. Among the diabetic patients who were screened according to the Short Musculoskeletal Function Assessment Questionnaire for musculoskeletal symptoms and findings, 82.6% were found to exhibit musculoskeletal abnormalities, mainly of the degenerative, noninflammatory type.

Conclusions: Musculoskeletal disorders are a common finding among patients with type 2 diabetes. Obesity and accumulation of abnormally glycosylated byproducts have been proposed as potential pathogenetic mediators of these connective tissue abnormalities. Of particular interest is, however, the common association of osteoarthritis, involving even non-weight bearing joints in patients with type 2 diabetes, indicating a common pathophysiologic mechanism connecting these two clinical conditions.

Keywords: diabetes mellitus; musculoskeletal disorders; prevalence.

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Figures

Figure 1.
Figure 1.. Prevalence of various non-inflammatory musculoskeletal disorders in type 2 diabetics
Figure 2.
Figure 2.. Prevalence of inflammatory musculoskeletal disorders in type 2 diabetics SLE: systemic lupus erythematosus, AS: ankylosing spondylitis, RA: rheumatoid arthritis, PsA: psoriatic arthritis
See this image and copyright information in PMC

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