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Comment
. 2009 Jul 15;15(14):4515-7.
doi: 10.1158/1078-0432.CCR-09-0873. Epub 2009 Jul 7.

Revealing tumor immunity after hematopoietic stem cell transplantation

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Revealing tumor immunity after hematopoietic stem cell transplantation

Catherine J Wu et al. Clin Cancer Res. .

Abstract

Allogeneic hematopoietic stem cell transplantation is currently the most effective method for inducing tumor immunity. However, the diversity of target antigens recognized by donor T cells has not been established. New studies show that tumor-reactive T cells are directed against diverse tumor-specific targets as well as minor histocompatibility antigens.

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