Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2009 Oct;13(5):505-10.
doi: 10.1007/s10029-009-0524-z. Epub 2009 Jul 10.

Fibrin sealant in inguinal hernioplasty: an observational multicentre study in 1,201 patients

B Descottes  1 , M Bagot d'Arc
Affiliations
Clinical Trial

Fibrin sealant in inguinal hernioplasty: an observational multicentre study in 1,201 patients

B Descottes et al. Hernia. 2009 Oct.

Abstract

Purpose: A prospective, multicentre, observational study was undertaken to assess Tisseel fibrin sealant for atraumatic mesh fixation in inguinal hernia repair throughout France.

Methods: Surgeons recorded data on patients undergoing tension-free inguinal hernioplasty with mesh fixation with Tisseel, regardless of the hernioplasty technique used. Assessments were made at 2 days and 1 month after surgery. Data on local complications, operation times and ease of product use were collected.

Results: In total, 1,201 patients were recruited (90% men, mean age 57 years), among which 526 procedures were performed using open techniques and 675 using laparoscopic repairs. Local complications occurred in 4.7% of patients: 3.0% haematoma, 1.4% seroma, 0.3% recurrence. The mean visual analogue scale (VAS)-rated pain scores were 3.2 pre-operatively, 2.3 immediately after surgery and 1.8 at 1 month. Surgeons rated the product as very easy to use.

Conclusions: Tisseel fibrin sealant appears to be a well-tolerated and easy-to-use alternative to traditional, tissue-penetrating devices for mesh fixation in hernia repair techniques.

PubMed Disclaimer

References

    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PubMed', 'value': '8497793', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/8497793/'}]}
    2. Rutkow IM, Robbins AW (1993) Demographic, classificatory, and socioeconomic aspects of hernia repair in the United States. Surg Clin North Am 73:413–426 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1016/0002-9610(87)90153-X', 'is_inner': False, 'url': 'https://doi.org/10.1016/0002-9610(87)90153-x'}, {'type': 'PubMed', 'value': '3296805', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/3296805/'}]}
    2. Lichtenstein IL (1987) Herniorrhaphy. A personal experience with 6,321 cases. Am J Surg 153:553–559 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'PMC', 'value': 'PMC8407507', 'is_inner': False, 'url': 'https://pmc.ncbi.nlm.nih.gov/articles/PMC8407507/'}, {'type': 'PubMed', 'value': '12535413', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/12535413/'}]}
    2. McCormack K, Scott NW, Go PM, Ross S, Grant AM; EU Hernia Trialists Collaboration (2003) Laparoscopic techniques versus open techniques for inguinal hernia repair. Cochrane Database Syst Rev 1:CD001785 - PMC - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1007/s10029-003-0144-y', 'is_inner': False, 'url': 'https://doi.org/10.1007/s10029-003-0144-y'}, {'type': 'PubMed', 'value': '12955591', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/12955591/'}]}
    2. Verstraete L, Swannet H (2003) Long-term follow-up after Lichtenstein hernioplasty in a general surgical unit. Hernia 7:185–190 - PubMed
    1. {'text': '', 'ref_index': 1, 'ids': [{'type': 'DOI', 'value': '10.1046/j.1365-2168.2002.02260.x', 'is_inner': False, 'url': 'https://doi.org/10.1046/j.1365-2168.2002.02260.x'}, {'type': 'PubMed', 'value': '12390395', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/12390395/'}]}
    2. Kumar S, Wilson RG, Nixon SJ, Macintyre IM (2002) Chronic pain after laparoscopic and open mesh repair of groin hernia. Br J Surg 89:1476–1479 - PubMed

Publication types

LinkOut - more resources