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Comparative Study
. 2009 Jun;80(3):330-3.
doi: 10.3109/17453670903066596.

C-reactive protein levels after 4 types of arthroplasty

Hao Shen  1 , Nanxin Zhang, Xianlong Zhang, Weiping Ji
Affiliations
Comparative Study

C-reactive protein levels after 4 types of arthroplasty

Hao Shen et al. Acta Orthop. 2009 Jun.

Abstract

Background and purpose: Postoperative C-reactive protein (CRP) levels in serum appear to reflect surgical trauma. We examined CRP levels after 4 types of arthroplasty.

Material and methods: We investigated 102 patients who had total knee arthroplasty (TKA), computer navigation-assisted total knee arthroplasty (NAV-TKA), hip resurfacing arthroplasty (metal on metal, MMSA) and total hip arthroplasty (THA), respectively. CRP levels were estimated before surgery and postoperatively at 2 and 7 days.

Results: Postoperatively, the peak CRP levels were highest on the second day after surgery in each of the groups. The peak CPR levels after hip resurfacing were lower than those after conventional primary THA. The peak CRP levels after computer navigation-assisted TKA were lower than those after conventional primary TKA.

Interpretation: The extent of bone and bone marrow injury rather than the region of surgery or the amount of soft tissue damage appears to determine the extent of the postoperative CRP response.

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Figures

Figure 3.
Figure 3.
CRP response after 4 different types of arthroplasty.
Figure 4.
Figure 4.
CRP peak levels of 4 types of arthroplasty on the second day. Each box indicates the median, 25, 75 percentiles and minimum and maximum values for each type of arthroplasty.
See this image and copyright information in PMC

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