Comment
doi: 10.1016/j.cell.2009.06.039.
Breaking up just got easier to do
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- PMID: 19596231
- DOI: 10.1016/j.cell.2009.06.039
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Comment
Breaking up just got easier to do
Cell.
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Free article
Abstract
The SLX4 protein functions as a platform for catalytic subunits of structure-specific endonucleases. Findings reported in Cell (Fekairi et al., 2009; Svendsen et al., 2009) and in Molecular Cell (Andersen et al., 2009; Muñoz et al., 2009) now identify the human SLX4 and show that in association with the SLX1 endonuclease it directs the symmetric cleavage and resolution of Holliday junctions.
Comment on
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Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.Cell. 2009 Jul 10;138(1):63-77. doi: 10.1016/j.cell.2009.06.030. Cell. 2009. PMID: 19596235 Free PMC article.
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Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.Cell. 2009 Jul 10;138(1):78-89. doi: 10.1016/j.cell.2009.06.029. Cell. 2009. PMID: 19596236 Free PMC article.
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