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. 1991 Nov;88(1):101-4.
doi: 10.1007/BF00204938.

The human cardiac troponin I locus: assignment to chromosome 19p13.2-19q13.2

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The human cardiac troponin I locus: assignment to chromosome 19p13.2-19q13.2

C MacGeoch et al. Hum Genet. 1991 Nov.

Abstract

The three major troponin I isoforms are encoded by separate genes and are expressed in a muscle-type-specific manner. A human cardiac troponin I cDNA has recently been isolated and used to establish the genomic location of the cardiac troponin I gene locus (designated TNNC1). By somatic cell hybrid analysis, the locus for TNNC1 maps to human chromosome 19 and can be localised to the region p13.2-q13.2.

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