Human- and virus-encoded microRNAs as potential targets of antiviral therapy
- PMID: 19601888
- DOI: 10.2174/138955709788681573
Human- and virus-encoded microRNAs as potential targets of antiviral therapy
Abstract
It has recently been demonstrated that short RNA molecules, called microRNAs, are one of the major factors regulating the expression of human genes. There are several lines of evidence that microRNAs also play a key role in host-virus interactions. It is believed that both human- and virus-encoded miRNA will, in the nearest future, become very attractive targets of antiviral therapy.
Similar articles
-
Role of virus-encoded microRNAs in Avian viral diseases.Viruses. 2014 Mar 21;6(3):1379-94. doi: 10.3390/v6031379. Viruses. 2014. PMID: 24662606 Free PMC article. Review.
-
The program of antiviral agents inhibits virus infection.Arch Microbiol. 2018 Aug;200(6):841-846. doi: 10.1007/s00203-018-1525-z. Epub 2018 May 30. Arch Microbiol. 2018. PMID: 29846759 Review.
-
vHoT: a database for predicting interspecies interactions between viral microRNA and host genomes.Arch Virol. 2012 Mar;157(3):497-501. doi: 10.1007/s00705-011-1181-y. Epub 2011 Dec 8. Arch Virol. 2012. PMID: 22160653
-
Cellular versus viral microRNAs in host-virus interaction.Nucleic Acids Res. 2009 Mar;37(4):1035-48. doi: 10.1093/nar/gkn1004. Epub 2008 Dec 18. Nucleic Acids Res. 2009. PMID: 19095692 Free PMC article. Review.
-
VIRmiRNA: a comprehensive resource for experimentally validated viral miRNAs and their targets.Database (Oxford). 2014 Nov 7;2014:bau103. doi: 10.1093/database/bau103. Print 2014. Database (Oxford). 2014. PMID: 25380780 Free PMC article.
Cited by
-
A new short oligonucleotide-based strategy for the precursor-specific regulation of microRNA processing by dicer.PLoS One. 2013 Oct 29;8(10):e77703. doi: 10.1371/journal.pone.0077703. eCollection 2013. PLoS One. 2013. PMID: 24204924 Free PMC article.
-
Roles of host and viral microRNAs in human cytomegalovirus biology.Virus Res. 2011 May;157(2):180-92. doi: 10.1016/j.virusres.2010.10.011. Epub 2010 Oct 20. Virus Res. 2011. PMID: 20969901 Free PMC article. Review.
-
Varicella-Zoster Virus Expresses Multiple Small Noncoding RNAs.J Virol. 2017 Nov 30;91(24):e01710-17. doi: 10.1128/JVI.01710-17. Print 2017 Dec 15. J Virol. 2017. PMID: 29021397 Free PMC article.
-
Six Medicago truncatula Dicer-like protein genes are expressed in plant cells and upregulated in nodules.Plant Cell Rep. 2016 May;35(5):1043-52. doi: 10.1007/s00299-016-1936-8. Epub 2016 Jan 29. Plant Cell Rep. 2016. PMID: 26825594 Free PMC article.
-
The many faces of Dicer: the complexity of the mechanisms regulating Dicer gene expression and enzyme activities.Nucleic Acids Res. 2015 May 19;43(9):4365-80. doi: 10.1093/nar/gkv328. Epub 2015 Apr 16. Nucleic Acids Res. 2015. PMID: 25883138 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources