Initiating antidepressant therapy? Try these 2 drugs first
- PMID: 19607774
- PMCID: PMC3183928
Initiating antidepressant therapy? Try these 2 drugs first
Abstract
When you initiate antidepressant therapy for patients who have not been treated for depression previously, select either sertraline or escitalopram. A large meta-analysis found these medications to be superior to other "new-generation" antidepressants.
Comment on
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Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis.Lancet. 2009 Feb 28;373(9665):746-58. doi: 10.1016/S0140-6736(09)60046-5. Lancet. 2009. PMID: 19185342 Review.
References
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- Cipriani A, Furukawa TA, Salanti G, et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet. 2009;373:746–758.. - PubMed
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- Murray CJ, Lopez AD. Global Burden of Disease. Cambridge, MA: Harvard University Press; 1996.
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- Williams SB, O’Connor EA, Eder M, et al. Screening for child and adolescent depression in primary care settings: a systematic evidence review for the U.S. Preventive Services Task Force. Pediatrics. 2009;123:e716–e735.. - PubMed
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- Gartlehner G, Hansen RA, Thieda P, et al. Comparative Effectiveness of Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression. Comparative Effectiveness Review No. 7. (Prepared by RTI International-University of North Carolina Evidence Based Practice Center under Contract No. 290-02-0016.) Rockville, MD: Agency for Healthcare Research and Quality; January 2007. Available at: www.effectivehealthcare.ahrq.gov/reports/final.cfm. Accessed May 18, 2009.
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