Baby got brain: Fgf10 sets rostral cortical size
- PMID: 19607785
- DOI: 10.1016/j.neuron.2009.06.015
Baby got brain: Fgf10 sets rostral cortical size
Abstract
Brain growth occurs throughout embryogenesis and early postnatal life, but its foundation is laid in the primitive neuroepithelium. In this issue of Neuron, Sahara and O'Leary identify Fgf10 as a key regulator of the neuroepithelial to radial glial transition and subsequently of size of the rostral forebrain.
Comment on
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Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors.Neuron. 2009 Jul 16;63(1):48-62. doi: 10.1016/j.neuron.2009.06.006. Neuron. 2009. PMID: 19607792 Free PMC article.
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