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. 2009 Oct;42(15):1561-4.
doi: 10.1016/j.clinbiochem.2009.07.008. Epub 2009 Jul 16.

Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4'-epimerase (GALE) activities

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Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4'-epimerase (GALE) activities

Irena Prodan-Zitnik et al. Clin Biochem. 2009 Oct.

Abstract

Objectives: The aim of our study was to determine whether the activities of galactose-1-phosphate uridyltransferase and UDP-galactose-4'-epimerase are correlated, and in what way they may influence one another.

Design and methods: Enzyme activities were measured in red blood cells from 214 individuals.

Results: A statistically significant (p<0.001) positive correlation was observed between GALT and GALE activities.

Conclusions: Our results suggest that GALT and GALE activities are correlated and that GALE activity has a greater impact on GALT activity than vice versa.

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