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Review
. 2009 Jul 23;6(1):1-2.
doi: 10.1016/j.chom.2009.07.001.

CarD tricks and magic spots: mechanisms of stringent control in mycobacteria

Lynn E Connolly  1 , Jeffery S Cox
Affiliations
Free article
Review

CarD tricks and magic spots: mechanisms of stringent control in mycobacteria

Lynn E Connolly et al. Cell Host Microbe. .
Free article

Abstract

Global reprogramming of bacterial gene expression in response to nutritional stress, the stringent response, is well studied in E. coli. Now Stallings et al. report that Mycobacterium tuberculosis employs a different strategy involving the general transcription factor CarD for growth control and persistence in response to stresses encountered during infection.

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