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Review
. 2009 Aug;20 Suppl 6(Suppl 6):vi1-7.
doi: 10.1093/annonc/mdp252.

Epidemiology of invasive cutaneous melanoma

R M MacKie  1 , A Hauschild, A M M Eggermont
Affiliations
Review

Epidemiology of invasive cutaneous melanoma

R M MacKie et al. Ann Oncol. 2009 Aug.

Abstract

Data are presented on the current incidence of melanoma with recent and predicted future trends illustrating a likely continuing increase in incidence. Risk factors for developing melanoma are discussed, including current known melanoma susceptibility genes. Phenotypic markers of high-risk subjects include high counts of benign melanocytic naevi. Other risk factors considered include exposure to natural and artificial ultraviolet radiation, the effect of female sex hormones, socioeconomic status, occupation, exposure to pesticides and ingestion of therapeutic drugs including immunosuppressives and non-steroidal anti-inflammatory drugs. Aids to earlier diagnosis are considered, including public education, screening and use of equipment such as the dermatoscope. Finally, the current pattern of survival and mortality is described.

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Figures

Figure 1.
Figure 1.
Age-standardised incidence and mortality rates of malignant melanoma in Great Britain between 1975 and 2005.
See this image and copyright information in PMC

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