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Comment
. 2009 Jul 21;106(29):11827-8.
doi: 10.1073/pnas.0906295106. Epub 2009 Jul 15.

Proviral protein provides placental function

Jonathan P Stoye  1
Affiliations
Comment

Proviral protein provides placental function

Jonathan P Stoye. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Consequences of Env–receptor interactions. (A) Retrovirus infection. After receptor binding, Env-mediated fusion between virus and cell membranes occurs, resulting in the uptake of viral cores into the cell cytoplasm. Precise details of the triggering of fusion, other factors involved, and the site of membrane fusion vary from virus to virus. (B) Restriction of virus entry. The product of a retrovirus-derived env gene interacts with receptor protein leading to the absence of free receptor on the cell surface thereby preventing infection. Where in the cell the receptor–Env interaction takes place and the mechanism of resistance, e,g. blocking or down-regulation from the cell surface, is likely to vary on a case-by-case basis. (C) Cell fusion. Env-mediated membrane fusion between two cells results in the formation of multinucleate cells.
See this image and copyright information in PMC

Comment on

References

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