A receptor for eating mitochondria
- PMID: 19619484
- DOI: 10.1016/j.devcel.2009.07.003
A receptor for eating mitochondria
Abstract
Mitochondria play central roles in cell survival by producing energy, and in cell death by regulating apoptosis. Conversely, the life and death of mitochondria, including growth, fission, and autophagic degradation, is controlled by the host cell. Using yeast genetics, a mitochondrial surface receptor involved in mitochondrial autophagy has recently been identified.
Comment on
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Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy.Dev Cell. 2009 Jul;17(1):87-97. doi: 10.1016/j.devcel.2009.06.013. Dev Cell. 2009. PMID: 19619494
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Atg32 is a mitochondrial protein that confers selectivity during mitophagy.Dev Cell. 2009 Jul;17(1):98-109. doi: 10.1016/j.devcel.2009.06.014. Dev Cell. 2009. PMID: 19619495 Free PMC article.
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