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Case Reports
. 2009 Aug;155(2):292-4.
doi: 10.1016/j.jpeds.2009.01.071.

Vascular perfusion abnormalities in infants with spinal muscular atrophy

Alexandra prufer de Queiroz Campos Araujo  1 , Mario Araujo, Kathryn J Swoboda
Affiliations
Case Reports

Vascular perfusion abnormalities in infants with spinal muscular atrophy

Alexandra prufer de Queiroz Campos Araujo et al. J Pediatr. 2009 Aug.

Abstract

Spinal muscular atrophy (SMA) is an important cause of death in children and SMA type I, also known as Werdnig-Hoffman disease, is the most severe form of this disease. We report 2 cases of infants with SMA I in whom a distal necrosis developed, a feature not previously reported. Poor perfusion, autonomic dysfunction, and position-dependent factors may all play a role in the development of this complication.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Digital necrosis.
Figure 2
Figure 2
The same patient after follow-up.
See this image and copyright information in PMC

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