Comment on

• Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection.

  Johnson AL, Aravind L, Shulzhenko N, Morgun A, Choi SY, Crockford TL, Lambe T, Domaschenz H, Kucharska EM, Zheng L, Vinuesa CG, Lenardo MJ, Goodnow CC, Cornall RJ, Schwartz RH. Johnson AL, et al. Nat Immunol. 2009 Aug;10(8):831-9. doi: 10.1038/ni.1769. Epub 2009 Jul 13. Nat Immunol. 2009. PMID: 19597497 Free PMC article.
• Themis, a T cell-specific protein important for late thymocyte development.

  Lesourne R, Uehara S, Lee J, Song KD, Li L, Pinkhasov J, Zhang Y, Weng NP, Wildt KF, Wang L, Bosselut R, Love PE. Lesourne R, et al. Nat Immunol. 2009 Aug;10(8):840-7. doi: 10.1038/ni.1768. Epub 2009 Jul 13. Nat Immunol. 2009. PMID: 19597498 Free PMC article.
• Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling.

  Fu G, Vallée S, Rybakin V, McGuire MV, Ampudia J, Brockmeyer C, Salek M, Fallen PR, Hoerter JA, Munshi A, Huang YH, Hu J, Fox HS, Sauer K, Acuto O, Gascoigne NR. Fu G, et al. Nat Immunol. 2009 Aug;10(8):848-56. doi: 10.1038/ni.1766. Epub 2009 Jul 13. Nat Immunol. 2009. PMID: 19597499 Free PMC article.