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. 2009 Jul 21;6(7):e1000106.
doi: 10.1371/journal.pmed.1000106. Epub 2009 Jul 21.

Focusing on quality patient care in the new global subsidy for malaria medicines

Affiliations

Focusing on quality patient care in the new global subsidy for malaria medicines

Suerie Moon et al. PLoS Med. .

Abstract

Tido von Schoen-Angerer and colleagues discuss the new Affordable Medicines Facility for malaria (AMFm), which subsidizes and facilitates access to artemisinin-based combination therapy, and what mechanisms are needed to ensure it stays focused on quality patient care.

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Conflict of interest statement

JMK was an unpaid member of the Committee on the Economics of Antimalarial Drugs for the Institute of Medicine 2004 report “Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance,” which first proposed a subsidy. JMK and TvSA have been consulted as stakeholders during the preparation of the technical proposal of the AMFm, but none of the authors had any role in the design nor any other official role.

Figures

Figure 1
Figure 1. Evolution of prices for ACT adult treatment.
Sources of prices are as follows: Artemether/lumefantrine (Novartis): Publicly announced prices by Novartis September 29, 2006 ; Novartis April 23, 2008 , and WHO May 16, 2007 . Artemether/lumefantrine (generic): Prices quoted to MSF (manufacturer: Ajanta) followed by prices announced by Clinton HIV/AIDS Initiative (manufacturers: Cipla, IPCA) July17, 2008 . Artesunate/amodiaquine FDC (DNDi/sanofi-aventis): Prices paid by MSF Logistique to manufacturer (MSF internal data). See also sanofi-aventis/DNDi announcement . Artesunate/amodiaquine co-blister average WHO/UNICEF co-tenders: average price from five tenders . Artemisinin (raw material): . The artemisinin raw material considered here as the quantity needed for production of one adult treatment course with artesunate/amodiaquine is 613 mg and 839 mg with artemether/lumefantrine (in both cases with 5% lost during manufacturing).

References

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