Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice

doi:10.1001/jama.2009.1073

Editorial

. 2009 Jul 22;302(4):436-7.

doi: 10.1001/jama.2009.1073.

Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice

Ronald C Petersen, John Q Trojanowski

PMID: 19622825
PMCID: PMC2792581
DOI: 10.1001/jama.2009.1073

Editorial

Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice

Ronald C Petersen et al. JAMA. 2009.

. 2009 Jul 22;302(4):436-7.

doi: 10.1001/jama.2009.1073.

Authors

Ronald C Petersen, John Q Trojanowski

PMID: 19622825
PMCID: PMC2792581
DOI: 10.1001/jama.2009.1073

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CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.
Mattsson N, Zetterberg H, Hansson O, Andreasen N, Parnetti L, Jonsson M, Herukka SK, van der Flier WM, Blankenstein MA, Ewers M, Rich K, Kaiser E, Verbeek M, Tsolaki M, Mulugeta E, Rosén E, Aarsland D, Visser PJ, Schröder J, Marcusson J, de Leon M, Hampel H, Scheltens P, Pirttilä T, Wallin A, Jönhagen ME, Minthon L, Winblad B, Blennow K. Mattsson N, et al. JAMA. 2009 Jul 22;302(4):385-93. doi: 10.1001/jama.2009.1064. JAMA. 2009. PMID: 19622817

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Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects.
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References

1. Jack CR, Jr, Lowe VJ, Weigand SD, et al. Alzheimer’s Disease Neuroimaging Initiative. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer’s disease: implications for sequence of pathological events in Alzheimer’s disease. Brain. 2009;132(pt5):1355–1365. - PMC - PubMed
1. Mattsson N, Zetterberg H, Hansson O, et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA. 2009;302(4):385–393. - PubMed
1. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56:303–308. - PubMed
1. Petersen RC, Doody R, Kurz A, et al. Current concepts in mild cognitive impairment. Archives of Neurology. 2001;58:1985–1992. - PubMed
1. Petersen RC. Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine. 2004;256:183–194. - PubMed

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[1] Jack CR, Jr, Lowe VJ, Weigand SD, et al. Alzheimer’s Disease Neuroimaging Initiative. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer’s disease: implications for sequence of pathological events in Alzheimer’s disease. Brain. 2009;132(pt5):1355–1365. - PMC - PubMed

[2] Jack CR, Jr, Lowe VJ, Weigand SD, et al. Alzheimer’s Disease Neuroimaging Initiative. Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer’s disease: implications for sequence of pathological events in Alzheimer’s disease. Brain. 2009;132(pt5):1355–1365. - PMC - PubMed

[3] Mattsson N, Zetterberg H, Hansson O, et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA. 2009;302(4):385–393. - PubMed

[4] Mattsson N, Zetterberg H, Hansson O, et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA. 2009;302(4):385–393. - PubMed

[5] Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56:303–308. - PubMed

[6] Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56:303–308. - PubMed

[7] Petersen RC, Doody R, Kurz A, et al. Current concepts in mild cognitive impairment. Archives of Neurology. 2001;58:1985–1992. - PubMed

[8] Petersen RC, Doody R, Kurz A, et al. Current concepts in mild cognitive impairment. Archives of Neurology. 2001;58:1985–1992. - PubMed

[9] Petersen RC. Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine. 2004;256:183–194. - PubMed

[10] Petersen RC. Mild cognitive impairment as a diagnostic entity. Journal of Internal Medicine. 2004;256:183–194. - PubMed

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Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice

Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice

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