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. 2009 Jul;15(7):1084-7.
doi: 10.3201/eid1507.090153.

Intergenogroup recombinant sapovirus in Japan, 2007-2008

Wisoot Chanit  1 , Aksara Thongprachum, Pattara Khamrin, Shoko Okitsu, Masashi Mizuguchi, Hiroshi Ushijima
Affiliations

Intergenogroup recombinant sapovirus in Japan, 2007-2008

Wisoot Chanit et al. Emerg Infect Dis. 2009 Jul.

Abstract

We investigated the incidence of sapovirus (SaV)-associated gastroenteritis in infants and children in Japan during 2007-2008 and characterized the diversity of SaV-positive strains. SaV was detected in 19 (4%) of 477 fecal specimens. The leading genogroup (79%, 15 cases) comprised intergenogroup recombinant SaVs (GII/GIV).

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Figures

Figure 1
Figure 1
Phylogenetic tree of nucleotide sequences of sapovirus (SaV) strains (shown in boldface). The tree was constructed from partial nucleotide sequences of the capsid region by using PEC strain (a porcine SaV) as an outgroup. The numbers on each branch indicate the bootstrap values. Scale bar indicates nucleotide substitutions per position. GenBank accession numbers of reference strains are as follows: Osaka07-767/08/JP (AB433785), Osaka/19-115/07/JP (AB327280), Sydney3/04/AU (DQ104357), CU050202/05/HK (DQ155647), Angelholm/SW278/04/SE (DQ125333), Chiba/000671/99/JP (AJ786349), 18/DCC/Tokyo/43/JP (AB236378), Yak2/00/JP (AB046353), Ehime1596/99/JP (AM049952), CU050107/05/HK (DQ155646), CMH044/03/03/THA (EF600796), St.Pertersburg/8214/05/RUS (FJ214057), Karachi/730/92/PK (AB126249), Hou7-1181/90/USA (AF435814), Osaka/5836/04/JP(AB242324), Karachi/872/91/PK (AB181231), Sapporo/82/JP (U65427), Manchester/93/UK (X86560), 12/DCC/Tokyo/44/JP (AB235380), 4724/Osaka/02/JP (AB180212), Stockholm/318/97/SE (AF194182), Mex14917/00/USA (AF435813), Karachi/867/93/PK (AB181132), Parkville/94/UK (U73124), Houston/90/USA (U95644), Karachi/1017/90/PK (AB181227), Arg39/95/ARG (AY289803), Lyon/598/97/F (AJ271056), London/29845/92/UK (U95645), Mex340/90/USA (AF435812), Cruise ship/00/USA (AY289804), Karachi/874/92/PK (AB181129), Karachi/928/94/PK (AB181128), 4408/Maizuru/03/JP (AB180209), and PEC (AF182760).
Figure 2
Figure 2
Phylogenetic analysis of the polymerase region (A) and the capsid region (B), showing the different genogroups (GI–GV). The sapovirus (SaV) isolates detected in the study are highlighted in boldface. The scale indicates nucleotide substitutions per position. The numbers in the branches indicate the bootstrap values. GenBank accession numbers of reference strains are as follows: C12 (AY603425), Mc10 (AY237420), Kushiro5 (AB455793), Mc2 (AY237419), Bristol (AJ249939), Dresden (AY694184), NK24 (AY646856), Ehime1107 (DQ058829), Yak2 (AB046353), and Yokohama/16/2007/JP (AB305049).
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