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. 2009 Jul;15(7):1119-22.
doi: 10.3201/eid1507.080716.

Recurrent lymphocytic meningitis positive for herpes simplex virus type 2

Katariina Kallio-Laine  1 , Mikko Seppänen, Hannu Kautiainen, Marja Liisa Lokki, Maija Lappalainen, Ville Valtonen, Markus Färkkilä, Eija Kalso
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Recurrent lymphocytic meningitis positive for herpes simplex virus type 2

Katariina Kallio-Laine et al. Emerg Infect Dis. 2009 Jul.

Abstract

We found the prevalence of recurrent lymphocytic meningitis associated with herpes simplex virus type 2 (HSV-2) was 2.2/100,000 population in Finland during 1996-2006, higher than previous estimates. PCR was most sensitive in detecting HSV-2 DNA from cerebrospinal fluid if the sample was taken 2-5 days after symptom onset.

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Figure
Figure
Kaplan-Meier curve showing cumulative proportions of the second recurrent lymphocytic meningitis episode (the time from the first episode to the first recurrence, years) in patients, Finland. 95% confidence intervals were obtained by bias-corrected bootstrapping.
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