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Review
. 2009 Nov;86(5):483-9.
doi: 10.1038/clpt.2009.135. Epub 2009 Jul 22.

Drug dosing in patients with impaired renal function

D C Brater  1
Affiliations
Review

Drug dosing in patients with impaired renal function

D C Brater. Clin Pharmacol Ther. 2009 Nov.

Abstract

Renal function can affect disposition and response to drugs in a variety of ways. This review discusses the principles underlying such responses, with particular emphasis on how changes in disposition parameters affect dosing decisions.

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