Ribavirin analogs
- PMID: 19628158
- DOI: 10.1016/j.cld.2009.05.006
Ribavirin analogs
Abstract
Ribavirin is ineffective against hepatitis C virus as mono-therapy but is critical in attaining both early virologic response and sustained virologic response when combined with pegylated interferon. Ribavirin has significant dose-limiting toxicities, the most important of which is hemolytic anemia. Taribavirin is a ribavirin pro-drug, which targets the liver and has less incidence of anemia, and it may be a promising alternative to ribavirin in the future.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
