Interrelationships between human immunodeficiency virus and cytomegalovirus
- PMID: 1963058
Interrelationships between human immunodeficiency virus and cytomegalovirus
Abstract
The herpesvirus cytomegalovirus (CMV) appears to be a selective opportunistic infection of AIDS patients, as demonstrated by its high prevalence in those diagnosed with AIDS and those at high risk for the disease. There are several features common to the two viruses, including infection of lymphoid cells, ability to remain latent and/or abortively infect host cells, sexual transmission, and immunosuppressive properties. Furthermore, the two viruses may uniquely interact at the molecular level through transactivation of heterologous genes by regulatory proteins from each virus. These two viruses may therefore establish a unique relationship within infected persons, with each virus contributing to the pathogenesis of the other.
Similar articles
-
Characteristics of cutaneous cytomegalovirus infection in non-acquired immune deficiency syndrome, immunocompromised patients.Br J Dermatol. 2006 Nov;155(5):977-82. doi: 10.1111/j.1365-2133.2006.07456.x. Br J Dermatol. 2006. PMID: 17034528
-
[An esophageal ulcer due to cytomegalovirus in a female patient infected with the human immunodeficiency virus without serious immunosuppression: is this an acquired immunodeficiency syndrome?].Med Clin (Barc). 1992 May 9;98(18):717-8. Med Clin (Barc). 1992. PMID: 1318483 Spanish. No abstract available.
-
Dynamics of cytomegalovirus (CMV)-specific T cells in HIV-1-infected individuals progressing to AIDS with CMV end-organ disease.J Infect Dis. 2005 Mar 15;191(6):873-80. doi: 10.1086/427828. Epub 2005 Jan 31. J Infect Dis. 2005. PMID: 15717261
-
The neuropathology of adult HIV infection.Rev Neurol (Paris). 1998 Dec;154(12):816-29. Rev Neurol (Paris). 1998. PMID: 9932303 Review.
-
HIV infection and AIDS.P N G Med J. 1996 Sep;39(3):174-80. P N G Med J. 1996. PMID: 9795558 Review.