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. 1990 Aug-Sep;5(7):228-32.

[Treatment of supratentorial glioma with intracarotid cisplatin and intravenous carmustine]

[Article in Spanish]
J Rebollo  1 , S Martín-Algarra, I Bilbao, J L Zubieta, F A Calvo, P de Castro, M A Pastor, C Viteri, J M Martínez Lage
Affiliations
  • PMID: 1963067

[Treatment of supratentorial glioma with intracarotid cisplatin and intravenous carmustine]

[Article in Spanish]
J Rebollo et al. Neurologia. 1990 Aug-Sep.

Abstract

We report the results of intracarotid (IC) cisplatinum and intravenous carmustine (BCNU) in 26 patients with supratentorial malignant glioma and recurrent low grade glioma. A response rate of 53.84% (95% confidence interval 33.3%-73.4%) was found. The median survival for the whole group was 11 months (range 3-70), with 35% of patients surviving for 2 years. At the present time, 5 patients are still alive, with a median follow up of 68 months (range 56-70). Neurological toxicity has been low and transient, being attributable to the technical degree of care in catheter positioning, cisplatin dosage and the technique of drug administration into the carotid artery.

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