Thiazole analog as stearoyl-CoA desaturase 1 inhibitor
- PMID: 19632834
- DOI: 10.1016/j.bmcl.2009.07.015
Thiazole analog as stearoyl-CoA desaturase 1 inhibitor
Abstract
SCD1 inhibition may represent a novel treatment for obesity, type-2 diabetes and related metabolic disorders. A prototype thiazole amide analog 13 (MF-152) was identified as an excellent tool in the study of SCD biology in animals.
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