PhyloDet: a scalable visualization tool for mapping multiple traits to large evolutionary trees
- PMID: 19633096
- PMCID: PMC2752614
- DOI: 10.1093/bioinformatics/btp454
PhyloDet: a scalable visualization tool for mapping multiple traits to large evolutionary trees
Abstract
Evolutionary biologists are often interested in finding correlations among biological traits across a number of species, as such correlations may lead to testable hypotheses about the underlying function. Because some species are more closely related than others, computing and visualizing these correlations must be done in the context of the evolutionary tree that relates species. In this note, we introduce PhyloDet (short for PhyloDetective), an evolutionary tree visualization tool that enables biologists to visualize multiple traits mapped to the tree.
Availability: http://research.microsoft.com/cue/phylodet/
Figures

Similar articles
-
Seevolution: visualizing chromosome evolution.Bioinformatics. 2009 Apr 1;25(7):960-1. doi: 10.1093/bioinformatics/btp096. Epub 2009 Feb 20. Bioinformatics. 2009. PMID: 19233896 Free PMC article.
-
PADRE: a package for analyzing and displaying reticulate evolution.Bioinformatics. 2009 May 1;25(9):1199-200. doi: 10.1093/bioinformatics/btp133. Epub 2009 Mar 5. Bioinformatics. 2009. PMID: 19269989
-
Phylo.io: Interactive Viewing and Comparison of Large Phylogenetic Trees on the Web.Mol Biol Evol. 2016 Aug;33(8):2163-6. doi: 10.1093/molbev/msw080. Epub 2016 Apr 19. Mol Biol Evol. 2016. PMID: 27189561 Free PMC article.
-
Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation.Bioinformatics. 2007 Jan 1;23(1):127-8. doi: 10.1093/bioinformatics/btl529. Epub 2006 Oct 18. Bioinformatics. 2007. PMID: 17050570
-
Inferring trees.Methods Mol Biol. 2008;452:287-309. doi: 10.1007/978-1-60327-159-2_14. Methods Mol Biol. 2008. PMID: 18566770 Review.
Cited by
-
Aardvark: Composite Visualizations of Trees, Time-Series, and Images.IEEE Trans Vis Comput Graph. 2025 Jan;31(1):1290-1300. doi: 10.1109/TVCG.2024.3456193. Epub 2024 Nov 25. IEEE Trans Vis Comput Graph. 2025. PMID: 39255114
-
Lineage: Visualizing Multivariate Clinical Data in Genealogy Graphs.IEEE Trans Vis Comput Graph. 2019 Mar;25(3):1543-1558. doi: 10.1109/TVCG.2018.2811488. Epub 2018 Mar 6. IEEE Trans Vis Comput Graph. 2019. PMID: 29993603 Free PMC article.
-
Juniper: A Tree+ Table Approach to Multivariate Graph Visualization.IEEE Trans Vis Comput Graph. 2018 Sep 3:10.1109/TVCG.2018.2865149. doi: 10.1109/TVCG.2018.2865149. Online ahead of print. IEEE Trans Vis Comput Graph. 2018. PMID: 30188828 Free PMC article.
-
Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.PLoS Comput Biol. 2008 Nov;4(11):e1000225. doi: 10.1371/journal.pcbi.1000225. Epub 2008 Nov 21. PLoS Comput Biol. 2008. PMID: 19023406 Free PMC article.
References
-
- Felsenstein J. Phylogenies and the comparative method. Am. Nat. 1985;125:1–15.
-
- Harrigan PR, et al. Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy. J. Infect. Dis. 2005;191:339–347. - PubMed
-
- Lee B, et al. MSR Tech Report MSR-TR-2008-97. Microsoft Research; 2008. Det. (Distance Encoded Tree): a scalable visualization tool for mapping multiple traits to large evolutionary trees. - PubMed