Alzheimer's Disease in Adults with Down Syndrome
- PMID: 19633729
- PMCID: PMC2714652
- DOI: 10.1016/S0074-7750(08)00004-9
Alzheimer's Disease in Adults with Down Syndrome
Figures


Similar articles
-
Neural correlates of episodic memory in adults with Down syndrome and Alzheimer's disease.Alzheimers Res Ther. 2022 Sep 3;14(1):123. doi: 10.1186/s13195-022-01064-x. Alzheimers Res Ther. 2022. PMID: 36057615 Free PMC article.
-
Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study.Lancet. 2020 Jun 27;395(10242):1988-1997. doi: 10.1016/S0140-6736(20)30689-9. Lancet. 2020. PMID: 32593336 Free PMC article.
-
Plasma and cerebrospinal fluid glial fibrillary acidic protein levels in adults with Down syndrome: a longitudinal cohort study.EBioMedicine. 2023 Apr;90:104547. doi: 10.1016/j.ebiom.2023.104547. Epub 2023 Mar 30. EBioMedicine. 2023. PMID: 37002988 Free PMC article.
-
Searching for new pharmacological targets for the treatment of Alzheimer's disease in Down syndrome.Eur J Pharmacol. 2017 Dec 15;817:7-19. doi: 10.1016/j.ejphar.2017.10.004. Epub 2017 Oct 5. Eur J Pharmacol. 2017. PMID: 28987272 Review.
-
Psychosocial Risk Factors for Alzheimer's Disease in Patients with Down Syndrome and Their Association with Brain Changes: A Narrative Review.Neurol Ther. 2022 Sep;11(3):931-953. doi: 10.1007/s40120-022-00361-9. Epub 2022 May 21. Neurol Ther. 2022. PMID: 35596914 Free PMC article. Review.
Cited by
-
Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer's disease-related dysregulation.Clin Epigenetics. 2019 Dec 16;11(1):195. doi: 10.1186/s13148-019-0787-x. Clin Epigenetics. 2019. PMID: 31843015 Free PMC article.
-
Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer's Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-DSR) Study.J Clin Med. 2021 Apr 28;10(9):1907. doi: 10.3390/jcm10091907. J Clin Med. 2021. PMID: 33924960 Free PMC article.
-
Prevalence and modifiable risk factors for dementia in persons with intellectual disabilities.Alzheimers Res Ther. 2023 Jul 18;15(1):125. doi: 10.1186/s13195-023-01270-1. Alzheimers Res Ther. 2023. PMID: 37464412 Free PMC article.
-
The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology.Alzheimers Dement (Amst). 2020 Aug 3;12(1):e12065. doi: 10.1002/dad2.12065. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 32775597 Free PMC article. Review.
-
Semantic Verbal Fluency Pattern, Dementia Rating Scores and Adaptive Behavior Correlate With Plasma Aβ42 Concentrations in Down Syndrome Young Adults.Front Behav Neurosci. 2015 Nov 18;9:301. doi: 10.3389/fnbeh.2015.00301. eCollection 2015. Front Behav Neurosci. 2015. PMID: 26635555 Free PMC article.
References
-
- Albert M, Cohen C. The Test for Severe Impairment: An instrument for the assessment of patients with severe cognitive dysfunction. Journal of the American Geriatrics Society. 1992;40:449–453. - PubMed
-
- Alzheimer’s Association. Alzheimer’s Disease Facts and Figures. Chicago, IL: Author; 2007. pp. 1–29.
-
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: Fourth Edition. Washington, DC: Author; 1994.
-
- Aylward EH, Burt DB, Thorpe LU, Lai F, Dalton A. Diagnosis of dementia in individuals with intellectual disability. Journal of Intellectual Disability Research. 1997;41:152–164. - PubMed
-
- Baddeley A. The episodic buffer: A new component of working memory? Trends in Cognitive Science. 2000;4:417–423. - PubMed
Grants and funding
LinkOut - more resources
Full Text Sources