Review
doi: 10.1016/s0065-2423(09)47004-5.
Personalized clinical laboratory diagnostics
Affiliations
- PMID: 19634778
- DOI: 10.1016/s0065-2423(09)47004-5
Item in Clipboard
Review
Personalized clinical laboratory diagnostics
Adv Clin Chem.
2009.
Abstract
Molecular diagnostics play an important role in development of personalized medicine and may be termed personalized diagnostics. This chapter shows the role of various diagnostic technologies in personalizing treatment. Besides polymerase chain reaction (PCR), several non-PCR methods, biochips/microarrays, and nanobiotechnologies play an important role. Technologies for biomarkers, single nucleotide polymorphisms (SNPs), and cytogenetics provide basic information for personalized medicine. Finally, integration of diagnostics with therapeutics is an important component of personalized medicine. Future challenges and prospects of personalized diagnostics are discussed.
Similar articles
-
Innovative diagnostic technologies and their significance for personalized medicine.Mol Diagn Ther. 2010 Jun 1;14(3):141-7. doi: 10.1007/BF03256366. Mol Diagn Ther. 2010. PMID: 20560675
-
Applications of nanobiotechnology in clinical diagnostics.Clin Chem. 2007 Nov;53(11):2002-9. doi: 10.1373/clinchem.2007.090795. Epub 2007 Sep 21. Clin Chem. 2007. PMID: 17890442 Review.
-
Nanotechnology in clinical laboratory diagnostics.Clin Chim Acta. 2005 Aug;358(1-2):37-54. doi: 10.1016/j.cccn.2005.03.014. Clin Chim Acta. 2005. PMID: 15890325 Review.
-
Role of Proteomics in the Development of Personalized Medicine.Adv Protein Chem Struct Biol. 2016;102:41-52. doi: 10.1016/bs.apcsb.2015.09.002. Epub 2015 Nov 11. Adv Protein Chem Struct Biol. 2016. PMID: 26827601 Review.
-
Applications of biochips: from diagnostics to personalized medicine.Curr Opin Drug Discov Devel. 2004 May;7(3):285-9. Curr Opin Drug Discov Devel. 2004. PMID: 15216931 Review.
Cited by
-
Innovative diagnostic technologies and their significance for personalized medicine.Mol Diagn Ther. 2010 Jun 1;14(3):141-7. doi: 10.1007/BF03256366. Mol Diagn Ther. 2010. PMID: 20560675
-
Transcriptional Systems Vaccinology Approaches for Vaccine Adjuvant Profiling.Vaccines (Basel). 2025 Jan 1;13(1):33. doi: 10.3390/vaccines13010033. Vaccines (Basel). 2025. PMID: 39852812 Free PMC article.
-
Personalized medicine in neurodegenerative diseases: how far away?Mol Diagn Ther. 2014 Feb;18(1):17-24. doi: 10.1007/s40291-013-0058-z. Mol Diagn Ther. 2014. PMID: 24122102 Review.
-
Recent Developments in Miniaturized PCR-Microchips, Microarrays and Microdroplets.EJIFCC. 2012 Oct 12;23(3):76-9. eCollection 2012 Oct. EJIFCC. 2012. PMID: 27683419 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Medical