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Case Reports
. 2010 Aug;30(10):1361-5.
doi: 10.1007/s00296-009-1059-4. Epub 2009 Jul 29.

Signal recognition particle (SRP) positive myositis in a patient with cryptogenic organizing pneumonia (COP)

Felix Wantke  1 , Meinhard Kneussl, Marianne Hubner, Kurt Derfler, Thomas Brücke, Sabine Schmaldienst
Affiliations
Case Reports

Signal recognition particle (SRP) positive myositis in a patient with cryptogenic organizing pneumonia (COP)

Felix Wantke et al. Rheumatol Int. 2010 Aug.

Abstract

We report of a 46-year-old female patient with cryptogen organizing pneumonia preceding the rare SRP positive necrotising myositis without cardiac involvement and no sign of dysphagia. Myositis showed full regression without oral immune suppression but with extracorporeal treatment, performed as a combined therapy of plasmaexchange and immunoadsorption. After 33-month of treatment, anti-SRP antibodies were not detectable any more.

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