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Comment
. 2009 Jul 30;63(2):141-3.
doi: 10.1016/j.neuron.2009.07.008.

Amyloid + activation = Alzheimer's?

William Jagust  1
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Amyloid + activation = Alzheimer's?

William Jagust. Neuron. .
Free article

Abstract

PET imaging of Alzheimer's disease (AD) patients demonstrates Abeta-protein accumulation in a default mode network. In this issue of Neuron, Sperling and colleagues show that cognitively intact individuals with Abeta in this network fail to deactivate it during memory tasks, a finding with important implications for cognitive aging and early detection of AD.

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