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Comparative Study
. 2009 Nov;155(5):668-72.e1-3.
doi: 10.1016/j.jpeds.2009.05.025. Epub 2009 Jul 29.

Glycemic control in youth with diabetes: the SEARCH for diabetes in Youth Study

Diana B Petitti  1 , Georgeanna J Klingensmith, Ronny A Bell, Jeanette S Andrews, Dana Dabelea, Giuseppina Imperatore, Santica Marcovina, Catherine Pihoker, Debra Standiford, Beth Waitzfelder, Elizabeth Mayer-Davis; SEARCH for Diabetes in Youth Study Group
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Comparative Study

Glycemic control in youth with diabetes: the SEARCH for diabetes in Youth Study

Diana B Petitti et al. J Pediatr. 2009 Nov.

Abstract

Objective: To assess correlates of glycemic control in a diverse population of children and youth with diabetes.

Study design: This was a cross-sectional analysis of data from a 6-center US study of diabetes in youth, including 3947 individuals with type 1 diabetes (T1D) and 552 with type 2 diabetes (T2D), using hemoglobin A(1c) (HbA(1c)) levels to assess glycemic control.

Results: HbA(1c) levels reflecting poor glycemic control (HbA(1c) >or= 9.5%) were found in 17% of youth with T1D and in 27% of those with T2D. African-American, American Indian, Hispanic, and Asian/Pacific Islander youth with T1D were significantly more likely to have higher HbA(1c) levels compared with non-Hispanic white youth (with respective rates for poor glycemic control of 36%, 52%, 27%, and 26% vs 12%). Similarly poor control in these 4 racial/ethnic groups was found in youth with T2D. Longer duration of diabetes was significantly associated with poorer glycemic control in youth with T1D and T2D.

Conclusions: The high percentage of US youth with HbA(1c) levels above the target value and with poor glycemic control indicates an urgent need for effective treatment strategies to improve metabolic status in youth with diabetes.

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References

    1. Diabetes Control and Complications Trial Research Group. . The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977–86. - PubMed
    1. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Lancet. 1998;352:837–53. - PubMed
    1. Diabetes Control and Complications Trial Research Group. . Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: Diabetes Control and Complications Trial. J Pediatr. 1994;125:177–88. - PubMed
    1. Nathan DM, Cleary PA, Backlund JY, Genuth SM, Lachin JM, Orchard TJ, et al. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med. 2005;353:2643–53. - PMC - PubMed
    1. Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008;358:2560–72. - PubMed

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