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Review
. 2009 Sep;39(5):348-53.
doi: 10.1053/j.semnuclmed.2009.03.001.

Multimodality imaging: beyond PET/CT and SPECT/CT

Simon R Cherry  1
Affiliations
Review

Multimodality imaging: beyond PET/CT and SPECT/CT

Simon R Cherry. Semin Nucl Med. 2009 Sep.

Abstract

Multimodality imaging with positron emission tomography/computed tomography (PET/CT) and single-photon emission computed tomography (SPECT)/CT has become commonplace in clinical practice and in preclinical and basic biomedical research. Do other combinations of imaging modalities have a similar potential to impact medical science and clinical medicine? Presently, the combination of PET or SPECT with magnetic resonance imaging (MRI) is an area of active research, while other, perhaps less obvious combinations, including CT/MRI and PET/optical also are being studied. In addition to the integration of the instrumentation, there are parallel developments in synthesizing imaging agents that can be viewed by multiple imaging modalities. Is the fusion of PET and SPECT with CT the ultimate answer in multimodality imaging, or is it just the first example of a more general trend toward harnessing the complementary nature of the different modalities on integrated imaging platforms?

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References

    1. Hasegawa BH, Gingold EL, Reilly SM, et al. Medical Imaging IV: Image Formation. vol 1231. Newport Beach, CA: SPIE; 1990. Description of a simultaneous emission-transmission CT system; pp. 50–60.
    1. Hasegawa BH, Lang TF, Brown JK, et al. Object-specific attenuation correction of SPECT with coorelated dual-energy X-ray CT. IEEE Trans Nucl Sci. 1993;40:1242–1252.
    1. Kalki K, Blankespoor SC, Brown JK, et al. Myocardial perfusion imaging with a combined X-ray CT and SPECT system. J Nucl Med. 1997;38:1535–1540. - PubMed
    1. Lacroix KJ, Tsui BMW, Hasegawa BH, et al. Investigation of the use of X-ray CT images for attenuation compensation in SPECT. IEEE Trans Nucl Sci. 1994;41:2793–2799.
    1. Lang TF, Hasegawa BH, Liew SC, et al. Description of a prototype emission-transmission computed-tomography imaging system. J Nucl Med. 1992;33:1881–1887. - PubMed

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