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. 2009 Jul;5(7):e1000424.
doi: 10.1371/journal.pcbi.1000424. Epub 2009 Jul 31.

A quick guide to organizing computational biology projects

Affiliations

A quick guide to organizing computational biology projects

William Stafford Noble. PLoS Comput Biol. 2009 Jul.
No abstract available

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Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Figure 1
Figure 1. Directory structure for a sample project.
Directory names are in large typeface, and filenames are in smaller typeface. Only a subset of the files are shown here. Note that the dates are formatted <year>-<month>-<day> so that they can be sorted in chronological order. The source code src/ms-analysis.c is compiled to create bin/ms-analysis and is documented in doc/ms-analysis.html. The README files in the data directories specify who downloaded the data files from what URL on what date. The driver script results/2009-01-15/runall automatically generates the three subdirectories split1, split2, and split3, corresponding to three cross-validation splits. The bin/parse-sqt.py script is called by both of the runall driver scripts.

References

    1. Butler D. A new leaf. Nature. 2005;436:20–21. - PubMed
    1. Schwab M, Karrenbach M, Claerbout J. Making scientific computations reproducible. Computing in Science and Engineering. 2000;2:61–67.
    1. Drake DD. ELN implementation challenges. Drug Discov Today. 2007;12:647–649. - PubMed
    1. Baxter SM, Day SW, Fetrow JS, Reisinger SJ. Scientific software development is not an oxymoron. PLoS Comput Biol. 2006;2:e87. doi: 10.1371/journal.pcbi.0020087. - DOI - PMC - PubMed
    1. Wilson GV. Where's the real bottleneck in scientific computing? Am Sci. 2006;94:5–6.

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