Leptin: taking the path less traveled
- PMID: 19656482
- DOI: 10.1016/j.cmet.2009.07.004
Leptin: taking the path less traveled
Abstract
The metabolic hormone leptin influences feeding and metabolism through action on a distributed brain network. In this issue, Leinninger et al. (2009) describe a novel lateral hypothalamic neuronal population that is responsive to leptin and interfaces with dopamine circuits.
Comment on
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Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.Cell Metab. 2009 Aug;10(2):89-98. doi: 10.1016/j.cmet.2009.06.011. Cell Metab. 2009. PMID: 19656487 Free PMC article.
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