Can a simple blood test quantify brain injury?
- PMID: 19664171
- PMCID: PMC2750138
- DOI: 10.1186/cc7929
Can a simple blood test quantify brain injury?
Abstract
Despite significant advances in neurocritical care, it remains difficult to precisely measure the extent of neurological injury in patients affected by stroke, trauma, or cardiac arrest. In the intensive care unit the extent of primary and secondary injury often eludes clinicians, making prognostication imprecise and difficult. Derwall and colleagues present their findings on the dynamics of serum S-100B protein levels in out-of-hospital cardiac arrest survivors. Their study suggests that elevation of S-100B reflects the severity of the primary hypoxic-ischemic insult.
Comment on
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Changes in S-100 protein serum levels in survivors of out-of-hospital cardiac arrest treated with mild therapeutic hypothermia: a prospective, observational study.Crit Care. 2009;13(2):R58. doi: 10.1186/cc7785. Epub 2009 Apr 16. Crit Care. 2009. PMID: 19368739 Free PMC article.
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