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Review
. 2009 Oct 20;381(1):1-18.
doi: 10.1016/j.ijpharm.2009.07.033. Epub 2009 Aug 5.

Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system

XiaWei Wei  1 , ChangYang Gong, MaLing Gou, ShaoZhi Fu, QingFa Guo, Shuai Shi, Feng Luo, Gang Guo, LiYan Qiu, ZhiYong Qian
Affiliations
Review

Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system

XiaWei Wei et al. Int J Pharm. .

Abstract

Poly(epsilon-caprolactone)-poly(ethylene glycol) (PCL-PEG) copolymers are important synthetic biomedical materials with amphiphilicity, controlled biodegradability, and great biocompatibility. They have great potential application in the fields of nanotechnology, tissue engineering, pharmaceutics, and medicinal chemistry. This review introduced several aspects of PCL-PEG copolymers, including synthetic chemistry, PCL-PEG micro/nanoparticles, PCL-PEG hydrogels, and physicochemical and toxicological properties.

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