Molecular targeting of cancer stem cells
- PMID: 19664981
- DOI: 10.1016/j.stem.2009.07.006
Molecular targeting of cancer stem cells
Abstract
Cancer stem cells may be important targets for new anticancer drugs. In two recent articles in Cell Stem Cell, Jin et al. (2009) and Hoey et al. (2009) provide proof of principle for this idea in experimental models of solid tumors and leukemias, respectively.
Comment on
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DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency.Cell Stem Cell. 2009 Aug 7;5(2):168-77. doi: 10.1016/j.stem.2009.05.019. Cell Stem Cell. 2009. PMID: 19664991
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