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Review
. 2009 Aug 10;186(3):313-5.
doi: 10.1083/jcb.200907041.

The H2BK123Rgument

John A Latham, Sharon Y R Dent
Review

The H2BK123Rgument

John A Latham et al. J Cell Biol. .

Abstract

The discovery of trans-regulation of histone H3K4 methylation by ubiquitination of histone H2BK123 generated much excitement in the field of chromatin biology. Recently, the veracity of this example of cross talk between histone modifications in yeast was challenged (Foster and Downs, 2009. J. Cell Biol. doi:10.1083/jcb.200812088) but ultimately reconfirmed in a study in this issue (Nakanishi et al., 2009. J. Cell Biol. doi:10.1083/jcb.200906005).

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