Sendai virus P gene produces multiple proteins from overlapping open reading frames
- PMID: 1966841
- DOI: 10.1159/000468762
Sendai virus P gene produces multiple proteins from overlapping open reading frames
Abstract
The Sendai virus P gene contains overlapping open reading frames (ORFs), and several unusual mechanisms are used to produce multiple proteins from all three ORFs of this gene. These include the use of a non-AUG start codon, leaky ribosomal scanning, what appears to be scanning-independent ribosomal initiation and/or ribosomal jumping, and a form of mRNA editing.
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